Product Description

The CleanPlex® Lynch Syndrome Panel is a pre-designed and made-to-order multiplex PCR / amplicon-based targeted sequencing (NGS) assay designed to examine the germline variants or mutations across 7 genes associated with Lynch Syndrome. The panel targets all the exonic regions of those genes and the flanking intronic sequences. Compatible with just 10 ng of DNA, sequencing-ready libraries can be prepared using a streamlined workflow in just 3 hours. The pre-designed panel is optimized in silico to deliver data with high on-target performance and high coverage uniformity to ensure efficient use of sequencing reads.

This product is made to order. Once we receive your order, we will synthesize the panel and the kit will contain CleanPlex Multiplex PCR Primers and CleanPlex Targeted Library Kit. CleanPlex Indexed PCR Primers and CleanMag® Magnetic Beads can be ordered separately to complete the workflow from input DNA to sequencing-ready NGS libraries.

Storage Temperature

Store at -20 °C.

For Research Use Only. Not for use in diagnostic procedures.

Gene List: 
APC, EPCAM, MLH1, MSH2, MSH6, MUTYH, PMS2

References: 
Mork ME, et al. Identification of MSH2 inversion of exons 1-7 in clinical evaluation of families with suspected Lynch syndrome. Fam Cancer. 2017 Jul;16(3):357-361.

Watson P, et al. The risk of extra-colonic, extra-endometrial cancer in the Lynch syndrome. Int J Cancer. 2008 Jul 15;123(2):444-449.

產(chǎn)品留言

標題

聯(lián)系人

聯(lián)系電話

內(nèi)容

驗證碼

點擊換一張

注：1.可以使用快捷鍵Alt+S或Ctrl+Enter發(fā)送信息!
2.如有必要,請您留下您的詳細聯(lián)系方式!