CleanPlex®周期性發燒綜合征面板是一種預先設計和定制的基于多重PCR /擴增子的靶向測序（NGS）分析方法，旨在檢查與周期性發燒綜合征相關的16個基因的種系變異或突變。該小組針對這些基因的所有外顯子區域和側翼內含子序列。僅需10 ng DNA即可兼容測序就緒的文庫，只需3個小時即可使用簡化的工作流程進行準備。預先設計的面板經過計算機優化，可提供具有高目標性能和高覆蓋均勻性的數據，以確保有效利用測序讀數。
該產品是定做的。收到您的訂單后，我們將合成面板，該套件將包含CleanPlex Multiplex PCR引物和CleanPlex Targeted Library Kit。可以分別訂購CleanPlex索引PCR引物和CleanMag®磁珠，以完成從輸入DNA到可測序的NGS文庫的工作流程。
貯存溫度
儲存在-20°C。
僅供研究使用。不用于診斷過程。
Gene List: ADA2, CARD14, ELANE, IL36RN, LPIN2, MEFV, MVK, NLRC4, NLRP12, NLRP3, NOD2, PSMB8, PSTPIP1, TNFAIP3, TNFRSF1A, TRNT1 References: Kaya et al. Coexistence of familial Mediterranean fever and juvenile idiopathic arthritis with osteoporosis successfully treated with etanercept. Intern Med. 2010;49:619–22. Zhang et al. Genomic variations of the mevalonate pathway in porokeratosis. Elife. 2015 Jul 23;4:e06322. Soylemezoglu et al. Unresponsiveness to colchicine therapy in patients with familial Mediterranean fever homozygous for the M694V mutation. J Rheumatol. 2010;37:182–9.
Gene List: ADA2, CARD14, ELANE, IL36RN, LPIN2, MEFV, MVK, NLRC4, NLRP12, NLRP3, NOD2, PSMB8, PSTPIP1, TNFAIP3, TNFRSF1A, TRNT1
References: Kaya et al. Coexistence of familial Mediterranean fever and juvenile idiopathic arthritis with osteoporosis successfully treated with etanercept. Intern Med. 2010;49:619–22.
Zhang et al. Genomic variations of the mevalonate pathway in porokeratosis. Elife. 2015 Jul 23;4:e06322.
Soylemezoglu et al. Unresponsiveness to colchicine therapy in patients with familial Mediterranean fever homozygous for the M694V mutation. J Rheumatol. 2010;37:182–9.